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Models

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Mice

Adgrf4-KO

Strain Name：B6;129S-Adgrf4tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00055

A Paqr9 gene knockout strain.

Mice

Mir21a-KO

Strain Name：B6;129S-Mir21atm1.2Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-00159

This Mir21a gene knockout strain was generated by crossing Mir21a-flox (NM-CKO-00051) mice with EIIa-Cre transgenic mice. Exon1 of Mir21a gene was removed.

Mice

Mrgprf-KO

Strain Name：B6;129S-Mrgprftm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00050

A Mrgprf gene knockout strain.

Mice

Lyzl4-KO

Strain Name：B6;129S-Lyzl4tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00006

A Lyzl4 gene knockout strain.

Mice

Cdkn2a-KO(p19-KO)

Strain Name：C57BL/6Smoc-Cdkn2aem2Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190633

Cdkn2a(p19) gene knockout mouse model was established by knockout exon1 of Cdkn2a-p19ARF transcript (Cdkn2a-202 transcript).

Mice

Snx3-KO

Strain Name：C57BL/6Smoc-Snx3em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201912

Snx3-KO mice (Stock No.NM-KO-201912) carry a knockout allele derived from the targeted deletion of exon 2-3. While Snx3-KO(2) mice(Stock No.NM-KO-210172）carrying the exon 3 deletion. It has been reported in the literature that homozygous for this gene knockout will die in the embryonic stage.

Mice

Snx3-KO(2)

Strain Name：C57BL/6Smoc-Snx3emSmoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-210172

Snx3-KO(2) mice(Stock No.NM-KO-210172） carry a knockout allele derived from the targeted deletion of exon 3. While Snx3-KO mice(Stock No.NM-KO-201912）carrying the exon 2-3 deletion. It has been reported in the literature that homozygous for this gene knockout will die in the embryonic stage.

Mice

Cdkn2a-KO(p16-KO)

Strain Name：C57BL/6Smoc-Cdkn2aem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-240239

Cdkn2a(p16) gene knockout mouse model was established by knockout exon1 of Cdkn2a-p16INK4a transcript (Cdkn2a-201 transcript).

Mice

hFCRN

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-hFcRn)Fcgrtem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00109
Validation Data：Presence  |  Publications：1piece

This FcRn humanized strain is established by mating endogenous mouse Fcgrt gene Knockout mice with R26-hFcRn(FCGRT) Knock-in mice. These FcRn humanized mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations. While hFCRN(2)(Stock No.NM-HU-190070) and hFCRN(3)(Stock No.NM-HU-2000032）mice function similarly to hFCRN mice,for more detailed information please contact our technical advisor.

Mice

Fah-KO(Rag2/IL2rg-KO/hSIRPA(2)/hCD47)

Strain Name：C57BL/6Smoc-Sirpaem1(hSIRPA)Cd47em1(hCD47)Rag2em1Il2rgem1Fahem1Smoc
Strain State：Developing | Cat. NO.：NM-KO-254190

By deleting exon 8 of the Fah gene in the existing strain Rag2/IL2rg-KO/hSIRPA(2)/hCD47 (NM-HU-2000019), a Fah gene knockout mouse model was established.

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