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Models

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Mice

ICR

Strain Name：Smoc:ICR
Strain State：Repository Live | Cat. NO.：SM-006

ICR mice have good reproductive performance, strong disease resistance, a gentle temperament, and are generally used for safety evaluation, pharmacological and toxicological research, aging research, surgical experiments, and so on. They are also suitable for surrogate suckling and false pregnancy.

Mice

BALB/c

Strain Name：BALB/cAnSmoc
Strain State：Repository Live | Cat. NO.：SM-003

BALB/c is one of the most widely used inbred lines in biomedical research, especially in immunology and infectious disease research. The incidence of breast tumors is about 10% to 20%. There is a certain number of ovarian, adrenal, pulmonary tumors, and leukemia that occurs. Lung cancer occurs in 26% of female mice and 29% of male mice. The incidence of leukemia is 12% in females and 10% in males. Blood pressure was the highest compared to other inbred mice and had spontaneous hypertension.

Mice

Ace2-2A-CreERT2

Strain Name：C57BL/6Smoc-Ace2em2(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200187

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ace2 gene stop codon site. Ace2 encodes angiotensin I converting enzyme 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful for studying lung injury and kidney disease caused by SARS coronavirus infection.

Mice

huPBMC-(NMG)

Strain Name：huPBMC-(NMG)
Strain State：Repository Live | Cat. NO.：NM-NSG-015

NMG mice are injected with human peripheral blood mononuclear cells (huPBMCs).

Mice

huHSC-(NMG)

Strain Name：huHSC-(NMG)
Strain State：Repository Live | Cat. NO.：NM-NSG-017

After irradiation, NMG mice are injected with CD34+ hematopoietic stem cells (CD34+ HSC).

Mice

Ube2k-KO

Strain Name：C57BL/6Smoc-Ube2Kem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191054

Exon 5-6 of Ube2k gene was deleted to generate Ube2k knockout mice.

Mice

Prkcb-KO

Strain Name：C57BL/6Smoc-Prkcbem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190859

Exon 2 of Prkcb gene was deleted to generate Prkcb knockout mice.

Mice

Uqcrc1-KO

Strain Name：C57BL/6Smoc-Uqcrc1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190896

Exon 3-4 of Uqcrc1 gene was deleted to generate Uqcrc1 knockout mice.

Mice

Uqcrc2-KO

Strain Name：C57BL/6Smoc-Uqcrc2em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190897

Exon 3-4 of Uqcrc2 gene was deleted to generate Uqcrc2 knockout mice.

Mice

hAppNL-G-F

Strain Name：C57BL/6Smoc-Apptm3(hAppNL-G-F)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000088

The endogenous mouse App gene was replaced by human AppNL-G-F.

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