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Models

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Mice

Sav1-Flox

Strain Name：C57BL/6Smoc-Sav1tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200011

These mice carry loxP sites flanking exon 3 of Sav1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Sav1 gene.

Mice

Prkar1a-Flox

Strain Name：C57BL/6Smoc-Prkar1atm1(flox)Smoc
Strain State：Developing | Cat. NO.：NM-CKO-240915

These strains carry loxP sites flanking exon 3 of Prkar1a gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Prkar1a gene.

Mice

Lmx1b-Flox

Strain Name：C57BL/6Smoc-Lmx1bem1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200117

These mice carry loxP sites flanking exon 4-6 of Lmx1b gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Lmx1b gene.

Mice

Tlr7-KO(BALB/c)

Strain Name：BALB/cAnSmoc-Tlr7em4Smoc
Strain State：Developing | Cat. NO.：NM-KO-200646

Exon 3 of Tlr7 gene was deleted to generate Tlr7 knockout mice.

Mice

Syn1-KO

Strain Name：C57BL/6Smoc-Syn1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191042

Exon 4 of Syn1 gene was deleted to generate Syn1 knockout mice.

Mice

ICR

Strain Name：Smoc:ICR
Strain State：Repository Live | Cat. NO.：SM-006

ICR mice have good reproductive performance, strong disease resistance, a gentle temperament, and are generally used for safety evaluation, pharmacological and toxicological research, aging research, surgical experiments, and so on. They are also suitable for surrogate suckling and false pregnancy.

Mice

BALB/c

Strain Name：BALB/cAnSmoc
Strain State：Repository Live | Cat. NO.：SM-003

BALB/c is one of the most widely used inbred lines in biomedical research, especially in immunology and infectious disease research. The incidence of breast tumors is about 10% to 20%. There is a certain number of ovarian, adrenal, pulmonary tumors, and leukemia that occurs. Lung cancer occurs in 26% of female mice and 29% of male mice. The incidence of leukemia is 12% in females and 10% in males. Blood pressure was the highest compared to other inbred mice and had spontaneous hypertension.

Mice

Ace2-2A-CreERT2

Strain Name：C57BL/6Smoc-Ace2em2(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200187

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ace2 gene stop codon site. Ace2 encodes angiotensin I converting enzyme 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful for studying lung injury and kidney disease caused by SARS coronavirus infection.

Mice

hAppNL-G-F

Strain Name：C57BL/6Smoc-Apptm3(hAppNL-G-F)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000088

The endogenous mouse App gene was replaced by human AppNL-G-F.

Mice

hAppNL-F

Strain Name：C57BL/6Smoc-Apptm3(hAppNL-F)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000087

The endogenous mouse App gene was replaced by human AppNL-F.

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