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Models

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Mice

ICR

Strain Name：ICR
Strain State：Repository Live | Cat. NO.：SM-006
Validation Data：Presence

ICR

Mice

BALB/c

Strain Name：BALB/cAnSmoc
Strain State：Repository Live | Cat. NO.：SM-003

BALB/c is one of the most widely used inbred lines in biomedical research, especially in immunology and infectious disease research. The incidence of breast tumors is about 10% to 20%. There is a certain number of ovarian, adrenal, pulmonary tumors, and leukemia that occurs. Lung cancer occurs in 26% of female mice and 29% of male mice. The incidence of leukemia is 12% in females and 10% in males. Blood pressure was the highest compared to other inbred mice and had spontaneous hypertension.

Mice

Ace2-2A-CreERT2

Strain Name：C57BL/6Smoc-Ace2em2(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200187
Validation Data：Presence

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ace2 gene stop codon site. Ace2 encodes angiotensin I converting enzyme 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful for studying lung injury and kidney disease caused by SARS coronavirus infection.

Mice

hAppNL-F

Strain Name：C57BL/6Smoc-Apptm3(hAppNL-F)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000087
Validation Data：Presence

The endogenous mouse App gene was replaced by human AppNL-F.

Mice

hAppNL-G-F

Strain Name：C57BL/6Smoc-Apptm3(hAppNL-G-F)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000088
Validation Data：Presence

The endogenous mouse App gene was replaced by human AppNL-G-F.

Mice

hTREM2

Strain Name：C57BL/6Smoc-Trem2tm4(hTRem2)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000083
Validation Data：Presence

The endogenous mouse Trem2 gene was replaced by human TREM2 gene.

Mice

huPBMC-(NMG)

Strain Name：huPBMC-(M-NSG)
Strain State：Repository Live | Cat. NO.：NM-NSG-015

NMG mice are injected with human peripheral blood mononuclear cells (huPBMCs).

Mice

Icosl-Flox

Strain Name：C57BL/6Smoc-Icoslem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200330

These mice carry loxP sites flanking exon 2-3 of Icosl gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Icosl gene.

Mice

Prkcd-KO

Strain Name：C57BL/6Smoc-Prkcdem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190860

Exon 3-5 of Prkcd gene was deleted to generate Prkcd knockout mice.

Mice

huHSC-(NMG)

Strain Name：huHSC-(M-NSG)
Strain State：Repository Live | Cat. NO.：NM-NSG-017
Publications：2piece

After irradiation, NMG mice are injected with CD34+ hematopoietic stem cells (CD34+ HSC).

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