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R26-CAG-LSL-Armc12-IRES-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sor^{em1(CAG-LSL-Armc12-IRES-tdTomato-Wpre-pA)Smoc}
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200290

A CAG-LSL-Armc12-IRES-tdTomato-Wpre-pA expression cassette was knocked into the Rosa26 locus via CRISPR/Cas9 mediated recombination.

R26-CAG-LSL-PyMT-IRES-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sor^{em1(CAG-LSL-PyMT-IRES-Luc-2A-EGFP-Wpre-polyA)Smoc}
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190111

These mice harbor a CAG-LSL-PyMT-IRES-Luc-2A-EGFP-Wpre-pA conditional expression cassette in mouse Rosa26 loci via CRISPR/Cas mediated homologous recombination.

R26-CAG-LSL-hFCGR3A-IRES-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sor^{tm1(SA-FRT-2xpolyA-CAG-FRT-loxp-stop-loxp-FCGR3A-IRES-tdTomato-WPRE-polyA)Smoc}
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200255

A SA-FRT-2xpolyA-CAG-FRT-loxp-stop-loxp-FCGR3A-IRES-tdTomato-WPRE-polyA expression cassette was knocked into the Rosa26 locus via CRISPR/Cas9 mediated recombination.

R26-CAG-LSL-Kras*G12C-IRES-Luc(BALB/c)

Strain Name：BALB/cAnSmoc-Gt(ROSA)26Sor^{em2(CAG-FRT-LSL-Kras(G12C)-IRES-Luciferase-polyA)Smoc}
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200324

A CAG-FRT-loxp-stop-loxp-Kras(G12C)-IRES-Luciferase-polyA expression cassette was knocked into the R26 locus via CRISPR/Cas9 mediated recombination.

Tigre-pTRE2-LSL-ZGX!EmGFP-2A-ZGX!TagGFP2-2A-ZGX!hrGFP-CAG-LSL-tTA2

Strain Name：C57BL/6Smoc-Igs7^{em1(2Xlns-pTRE2-Lox2272-stop-Lox2272-ZGX!emGFP-T2A-ZGX!TagGFP2-P2A-ZGX!hrGFP-Wpre-pA-2Xlns-pCAG-LoxP-stop-LoxP-tTA2-Wpre-pA)Smoc}
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200288

A 2Xlns-pTRE2-Lox2272-stop-Lox2272-ZGX!EmGFP-T2A-ZGX!TagGFP2-P2A-ZGX!hrGFP- Wpre-pA-2Xlns-pCAG-LoxP-stop-LoxP-tTA2-Wpre-pA expression cassette was knocked into the TIGRE locus via CRISPR/Cas9 mediated recombination.

F8-KO(SD)

Strain Name：SD-F8^em1Smoc Strain State：Repository Live | Cat. NO.：NR-KO-200003
Validation Data：Presence

Using CRISPR/Cas9 technology, exon 16 of F8 gene was deleted to generate F8 knockout rat.

Foxn1-KO(SD)

Strain Name：SD-Foxn1^em1Smoc Strain State：Embryo cryopreservation | Cat. NO.：NR-KO-190002

Using CRISPR/Cas9 technology, Exon 2-4 of Foxn1 gene was deleted to generate Foxn1 knockout rat.

CRISPR/Cas9-mediated somatic and germline gene correction to restore hemostasis in hemophilia B mice

Model Organisms：小鼠 Product & Service：F9 Research field：hemophilia

CRISPR/Cas9‑mediated somatic and germline gene correction to restore hemostasis in hemophilia B mice

Model Organisms：Mouse Product & Service：F9 Research field：Hemophilia

Genome editing with CRISPR/Cas9 in postnatal mice corrects PRKAG2 cardiac syndrome

Model Organisms：小鼠 Product & Service：PRKAG2 H530R Research field：Heart

室性心律失常 AAV9 基因治疗