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Models

About 98 results
Mice

Amhr2-IRES-CreERT2

Strain Name：C57BL/6Smoc-Amhr2em(IRES-2A-CreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-204995

IRES-2A-CreERT2 expression cassette was knocked into the Amhr2 gene via CRISPR/Cas9 mediated recombination.

Mice

Il2-HiBiT

Strain Name：C57BL/6Smoc-Il2em1(HiBiT-tag)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200330

HiBiT was knocked into the stop coden of interleukin 2 gene via CRISPR/Cas9 mediated recombination.

Mice

Ifnb-HiBiT

Strain Name：C57BL/6Smoc-Ifnbem1(HiBiT-tag)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200329

HiBiT was knocked into the stop coden of interferon beta 1 gene via CRISPR/Cas9 mediated recombination.

Mice

Trp63-CreERT2

Strain Name：C57BL/6Smoc-Trp63em(CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225021

A CreERT2-Wpre-polyA expression cassette was knocked into the exon4 of Trp63 gene via CRISPR/Cas mediated recombination.

Mice

Cyp2e1-CreERT2

Strain Name：C57BL/6Smoc-Cyp2e1em1(CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-00047

A kozak-CreERT2-Wpre-polyA cassette was inserted at ATG site of Cyp2e1 gene via CRISPR/Cas mediated recombination.

Mice

R26-CAG-2xKRAB-dCas9-IRES-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-Loxp-2xKRAB-dCas9-IRES-EGFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18007

These mice harbor a CAG-LSL-2xKRAB-dCas9-IRES-EGFP-WPRE-pA conditional expression cassette in mouse Rosa26 loci via homologous recombination. This strain can be used in CRISPR mediated target gene transcriptional inhibition (CRISPRi). The loxp-stop-loxp cassette was deleted.

Mice

R26-CAG-LSL-dCas9-VPR-IRES-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-dCas9-VPR-IRES-EGFP-WPRE-pA)
Strain State：Repository Live | Cat. NO.：NM-KI-18004

These mice harbor a CAG-LSL-dCas9-VPR(VP64-p65-Rta)-eGFP-pA conditional expression cassette in mouse Rosa26 loci. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa).

Mice

Col1a1-TRE3G-dCas9-VPR-EGFP

Strain Name：C57BL/6Smoc-Col1a1em1(TRE3G-dCas9-VPR-eGFP-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00123

These mice harbor a TRE3G-dCas9-VPR(VP64-p65-Rta)-eGFP-pA tetracycline-controlled transcriptional activation cassette in mouse Col1a1 loci. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa).

Mice

Ighg1-HiBiT

Strain Name：C57BL/6Smoc-Ighg1em1(HiBiT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200275

HiBiT expression cassette was knocked into the Ighg1 gene stop codon site via CRISPR/Cas9 mediated recombination.

Mice

Abcb1a/Abcb1b-KO(FVB)

Strain Name：FVB-Abcb1aem1Abcb1bem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-191211

All sequences between exon2 of Abcb1a gene and exon28 of Abcb1b gene were knocked out by CRISPR/Cas9 technology.

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