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We Will Be Attending AACR 2023 in Orlando!

Workshop：Progress and Advances in Preclinical immuno-Oncology Research

SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.

These Mice Are About to Go Viral Because of the Nobel Prize!

microRNA (miRNA) microRNA mouse models Nobel Prize microRNA discovery genetically engineered mice miRNA in gene regulation miRNA therapeutics miRNA in cancer research customized mouse models contract research organization (CRO) preclinical drug discovery

The 2024 Nobel Prize in Physiology or Medicine awarded to Victor Ambros and Gary Ruvkun for their discovery of microRNA (miRNA) highlights its revolutionary role in gene regulation and disease treatment. This article explores miRNA's impact on neuroscience, cancer, and cardiovascular research. GenoBioTX offers advanced microRNA mouse models and customized genetic solutions, empowering researchers with essential tools to drive innovation in miRNA studies and therapeutic developments.

News Update: GenoBioTX and Crown Bioscience Sign Global Cooperation Agreement

Webinar on Advances in Antibody-Drug Conjugates (ADCs) Development & Preclinical Models

Antibody-Drug Conjugates ADC Development Preclinical Models Targeted Cancer Therapies GenoBioTX ADC Webinar Biopharma Research Oncology Biochemistry Cancer Treatment Preclinical Evaluation Monoclonal Antibodies Small Molecule Drugs

Join us for a webinar on June 26th, 2024, exploring the development and preclinical evaluation of Antibody-Drug Conjugates (ADCs). Learn from Dr. Hua Wei, VP of the Industrial Clients Department at GenoBioTX, about ADC components, mechanisms, historical evolution, and future directions.

Cancer Model

research on cancer cancer model mouse models of cancer

The laboratory mouse is widely considered as a valid and affordable model organism for studying human disease. Mouse models of cancer not only enable researchers to understand the genetic basis of tumor development in complicated and dynamic physiological systems, but also serve as irreplaceable tools for developing and testing new therapies.  Shanghai Model Organisms Center offers a variety of mouse models of cancer to meet the needs of both academic and industry partners.

Mouse models for cancer research

Tumor bearing Mouse DEN model PDX model CDX model

Shanghai Model Organisms Center provides multiple types of tumor-bearing mouse models for cancer research and drug efficacy testing, including cell line-derived xenograft model (CDX) and patient-derived xenograft model (PDX). While PDX models better reflect the heterogeneity and diversity of human cancers, CDX models allow researchers to advance their pre-clinical drug development in a cost- and time-efficient manner.

Research on Diseases

genetics diseases studies diseases research diseases

Shanghai Model Organisms provides a professional R&D platform for genetically-engineered mouse, zebrafish and nematode models, a service platform for phenotyping, and a rich repository of disease mouse models to support your studies on disease genetics, pathogenesis, drug treatments, and more.

Surgical & Preconditioning Services

Liver Cancer PDX Model

PDX PDX models Patient-derived Xenografts

Patient-derived Xenografts (PDX) are advanced preclinical oncology models for drug development. It offers a far better alternative for preclinical drug evaluation as compared to the conventional cell line-derived xenograft model.