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Mice

Kdm6b-Flox

Strain Name：C57BL/6Smoc-Kdm6bem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200113

These mice carry loxP sites flanking exon 14-20 of Kdm6b gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Kdm6b gene.

Mice

Dicer1-Flox

Strain Name：C57BL/6Smoc-Dicer1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200158

These mice carry loxP sites flanking exon 23 of Dicer1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Dicer1 gene.

Mice

Nkx2-1-CreERT2

Strain Name：C57BL/6Smoc-Nkx2-1em1(CreERT2-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200123

A CreERT2-pA expression cassette was knocked into the Nkx2-1 gene start codon site. Nkx2-1, a key molecule in lung development, is expressed in adult bronchial and alveolar type Ⅱ epithelial cells. Besides, Nkx2-1 expression as a prognostic marker is also been applied to lung cancer research including lung adenocarcinoma.

Mice

Foxn1-IRES-Cre

Strain Name：C57BL/6Smoc-Foxn1em1(IRES-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200106

A IRES-iCre expression cassette was knocked into the Foxn1 gene stop codon site. The protein encoded by Foxn1 (forkhead box N1) gene is part of the forkhead family or transcription factors that are important in developmental processes, immune system regulation, metabolism, cancer and aging. When crossed with a strain carrying a gene flanked by sites, the flanked gene will be removed in thymic epithelial cell and keratinocytes.

Mice

BALB/c

Strain Name：BALB/cAnSmoc
Strain State：Repository Live | Cat. NO.：SM-003

BALB/c is one of the most widely used inbred lines in biomedical research, especially in immunology and infectious disease research. The incidence of breast tumors is about 10% to 20%. There is a certain number of ovarian, adrenal, pulmonary tumors, and leukemia that occurs. Lung cancer occurs in 26% of female mice and 29% of male mice. The incidence of leukemia is 12% in females and 10% in males. Blood pressure was the highest compared to other inbred mice and had spontaneous hypertension.

Mice

Eif4b-KO

Strain Name：C57BL/6Smoc-Eif4Bem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191114

Exon 3-4 of Eif4b gene was deleted to generate Eif4b knockout mice.

Mice

Cab39l-KO

Strain Name：C57BL/6Smoc-Cab39Lem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191104

Exon 5-6 of Cab39l gene was deleted to generate Cab39l knockout mice.

Mice

hB7H3

Strain Name：C57BL/6Smoc-Cd276tm2(hB7H3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00107

The endogenous mouse Cd276 gene was replaced by human CD276 gene.

Mice

Btg2-KO

Strain Name：C57BL/6Smoc-Btg2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200587

Exon 2 of Btg2 gene was deleted to generate Btg2 knockout mice.

Mice

Mmp7-KO

Strain Name：C57BL/6Smoc-Mmp7em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190699

Exon 4-6 of Mmp7 gene was deleted to generate Mmp7 knockout mice.

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