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Mouse models for cancer research

Tumor bearing Mouse DEN model PDX model CDX model

Shanghai Model Organisms Center provides multiple types of tumor-bearing mouse models for cancer research and drug efficacy testing, including cell line-derived xenograft model (CDX) and patient-derived xenograft model (PDX). While PDX models better reflect the heterogeneity and diversity of human cancers, CDX models allow researchers to advance their pre-clinical drug development in a cost- and time-efficient manner.

Health Report

animal health report

Shanghai Model Organisms Center (SMOC) provides you with model mice that have been raised under specific pathogen-free (SPF) barriers. Since obtaining AAALAC-accreditation in 2012, Shanghai Model Organisms Center Co., Ltd. has adhered to the standards outlined in the Guide for the Care and Use of Laboratory Animals (Guide). You can download the monthly mice health report here.

Imaging Analysis

Animal imaging micro CT

shanghai Model Organisms provides services for microCT and IVIS whole-body in vivo imaging/fluorescence quantitative analysis of small animals.

Behavioral Analysis

study of animal behavior behavioral analysis

Shanghai Model Organisms' rodent behavioral analysis platform is equipped with a variety of experimental instruments used to study the classical behaviors of mice. Shanghai Model Organisms can provide single-item or complete sets of mouse behavioral analysis to assist you with your research in neurology, physiology, drug development, and drug efficacy evaluation. The Noldus behavioral analysis system is used to more comprehensively and accurately reflect the neurological and mental states of mice.

Mouse

transgenic mice mouse model editing mouse

Mice have long been the prime choice for model organisms. In more than 100 years, mice have been widely used by researchers in the fields of physiology, pathology, pharmacology, toxicology, and behavioral science. With the establishment of gene targeting technology, many researchers have made their way to the Nobel Prize.

Pathological Analysis

Pathological analysis H&E staining

Shanghai Model Organisms can analyze morphological and pathological changes in various animal tissues.

Gene overexpression

gene overexpression gene overexpression protocol gene overexpression techniques

Generate a mouse model in which an exogenous gene is introduced and overexpressed. An overexpression model can be used to investigate gene functions, promoter functions, or model the pathogenesis of human disease. Depending on the method to introduce foreign DNA, a random transgenes or targeted conditional overexpression model can be created.

EAE animal model

Some Basics about Cre-lox and Inducible Cre in Mouse Modeling

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