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Models

About 80 results
Mice

hBCMA/hCD3EDG/hCD19

Strain Name:C57BL/6Smoc-Tnfrsf17em1(hBCMA)Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd19em1(hCD19)Smoc
Strain State:Developing | Cat. NO.:NM-XA-242443

The hCD3EDG/hCD19(NM-HU-220109) was crossed with hBCMA(NM-HU-200228) to generate hBCMA/hCD3EDG/hCD19 mice.

Mice

hBCMA/hCD3EDG/hCD38

Strain Name:C57BL/6Smoc-Tnfrsf17em1(hBCMA)Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd38em2(hCD38)Smoc
Strain State:Developing | Cat. NO.:NM-XA-242724

The hCD3EDG/hCD38(2)(NM-HU-220114) was crossed with hBCMA(NM-HU-200228) to generate hBCMA/hCD3EDG/hCD38 mice.

Mice

hTNFRSF17/hCD3EDG(BALB/c)

Strain Name:BALB/cAnSmoc-Tnfrsf17em1(hTNFRSF17)Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Smoc
Strain State:Developing | Cat. NO.:NM-XA-250066

The hCD3EDG(BALB/c)(NM-HU-220122) was crossed with hTNFRSF17(BALB/c)(NM-HU-241173) to generate hTNFRSF17/hCD3EDG(BALB/c) mice.

Mice

hTIGIT/hTNFR2

Strain Name:C57BL/6Smoc-Tigittm3(hTIGIT)Tnfrsf1bem2(hTNFRSF1B)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210371

hTIGIT(3)(NM-HU-200244) was crossed with hTNFRSF1B(NM-HU-190010)to generate hTIGIT(3)/hTNFRSF1B mice

Rats

Ngfr-KO(SD)

Strain Name:SD-Ngfrem1Smoc Strain State:Embryo cryopreservation | Cat. NO.:NR-KO-210150

Exon2-3 of Ngfr gene was deleted to generate Ngfr knockout rats.

Cells

CT26-hTNFRSF1B

Strain Name:CT26-hTNFRSF1B
Strain State : Validation of tumorigenic capacity completed |  Cat. NO.:NMC-230002

TNFRSF1B gene humanized CT26 cell line

Cells

CT26-hTNFRSF1B(BSD)

Strain Name:CT26-hTNFRSF1B(BSD)
Strain State : Validation of target gene expression completed |  Cat. NO.:NMC-230079

TNFRSF1B gene humanized CT26 cell line

Cells

MC38-hTNFR2

Strain Name:MC38-hTNFR2
Strain State : Validation of tumorigenic capacity completed |  Cat. NO.:NMC-230001

TNFRSF1B gene humanized MC38 cell line

Pages

Osteoporosis

osteoporosis gene osteoporosis diseases Tnfrsf11b

Tnfrsf11b (Opg) knockout mice were generated through homologous recombination and supplied by Shanghai Research Center for Model Organisms. This mouse model, which is referred to as the "osteoporotic mouse", shows a typical phenotype of osteoporosis and arterial calcification, and Therefore, this animal model is ideal for drug screening and evaluation for the treatment of "human osteoporosis", in gene therapy of osteoporosis, as well as in the research on the mechanisms of interaction between osteoclasts and osteoblasts.

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