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Models

About 19,515 results
Mice

Ddx58-KO(2)

Strain Name：C57BL/6Smoc-Ddx58em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18063

Ddx58-KO(2) mice (Stock No.NM-KO-18063）carry a knockout allele derived from the targeted deletion of exon 4-7. While Ddx58-KO mice (Stock No.NM-KO-00063) have been pulled from shelves for some reasons.

Mice

Ciita-KO(2)

Strain Name：C57BL/6Smoc-Ciitaem2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191207

Ciita-KO(2) mice (Stock No.NM-KO-191207） carry a knockout allele derived from the targeted deletion of exon 6-10. While Ciita-KO mice (Stock No.NM-KO-190056) have been pulled from shelves for some reasons.

Mice

Tlr3-KO(2)

Strain Name：C57BL/6Smoc-Tlr3em2Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190431

Tlr3-KO(2) mice (Stock No.NM-KO-190431） carry a knockout allele derived from the targeted deletion of exon 4-7. While Tlr3-KO mice (Stock No.NM-KO-190164) have been pulled from shelves for some reasons.

Mice

Chrna7/Fan1-KO

Strain Name：C57BL/6Smoc-Chrna7em1(Del1263751bp)Fan1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18062

Exon 1-9 of Chrna7 gene and exon 5-14 of Fan1 gene were deleted to generate Chrna7/Fan1-KO mice.

Mice

hGIPR/Glp1r-KO

Strain Name：C57BL/6Smoc-Giprtm1(hGIPR)SmocGlp1rem1
Strain State：Repository Live | Cat. NO.：NM-XA-252329

The hGIPR (NM-HU-225064) was crossed with Glp1r-KO(NM-KO-190803) to generate hGIPR/Glp1r-KO mice.

Mice

hGLP1R/Gipr-KO

Strain Name：C57BL/6Smoc-Glp1rem2(hGLP1R)SmocGiprem1
Strain State：Repository Live | Cat. NO.：NM-XA-252330

The hGLP1R (NM-HU-200220) was crossed with Gipr-KO(NM-KO-200225) to generate hGLP1R/Gipr-KO mice.

Mice

hCRBN/Rag2-KO

Strain Name：C57BL/6Smoc-Crbntm1(hCRBN)SmocRag2em2
Strain State：Repository Live | Cat. NO.：NM-XA-251818

The hCRBN (NM-HU-225071) was crossed with Rag2-KO(NM-KO-190429) to generate hCRBN/Rag2-KO mice.

Mice

Rag2/F8-KO

Strain Name：C57BL/6Smoc-Rag2em2F8tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-220025

Rag2-KO(NM-KO-190429) was crossed with F8-KO(NM-KO-00012) to generate Rag2/F8-KO mice.

Mice

Crbn-I391V/Rag2-KO

Strain Name：C57BL/6Smoc-Crbnem1(I391V)Rag2em2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210398

Crbn-I391V(NM-KI-200331) was crossed with Rag2-KO(NM-KO-190429) to generate Crbn-I391V/Rag2-KO mice.

Mice

F9-KO

Strain Name：C57BL/6Smoc-F9em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18046

The F9 gene is located on the X chromosome. In this F9 knockout mouse model, gRNAs were designed targeting Exon8 of F9 gene via CRISPR gene editing technology. Loss of F9 caused coagulopathy in mice. Mice that are homozygous for F9 knockout are viable, fertile and normal in size. Normal fighting in the cage may cause bleeding or even death due to massive internal hemorrhaging. After the tail cutting, wounds must be cauterized to prevent homozygous knockout mice from blood loss and death. This strain is a powerful model for studying coagulopathy, gene therapy methods and function of factor IX mutations. F9-KO mice (Stock No.NM-KO-18046）carry a knockout allele derived from the targeted deletion of exon 8. While F9-KO(2) mice (Stock No.NM-KO-200607) carrying the exon 1-8 deletion.

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