Excision and Regeneration of Tissue
Principle Major gastric resection (sleeve gastrectomy) in diabetic mice can simulate the conditions observed in type II diabetes patients after clinical treatment.
Sample requirements Adult diabetic mice
Service cycle Surgery for 1 day. It is recommended to place the mice under observation for 1 week until their conditions become stable before delivery (with a certain rate of mortality).
Technical indicators The testing services including fasting blood glucose data, body weight data, GTT, and ITT.
Figure 1. Modeling method
Principle The mechanisms underlying liver regeneration and repair are studied by partial hepatectomy.
Sample requirements Male C57 mice of 10 weeks old
Service cycle 14 business days
Technical indicators Testing services include 1) Serum testing: biochemistry, ELISA; 2) Pathological testing: HE staining; 3) Detection of mRNA level: Real-time PCR; 4) Detection of protein level: Western blot, FACS.
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SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.
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