Models

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210358
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)Pdcd1em1(hPDCD1)Cd274em2(hPD-L1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220029
Mice
Strain Name:C57BL/6Smoc-Sirpaem2(hSIRPA)Cd274em1(hCD274)Cd47em1(hCD47)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000095
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:BALB/cAnSmoc-Sirpaem(hSIRPA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210369
Research Application:inmmue therapy;drug screening
Mice
Strain Name:BALB/cAnSmoc-Sirpaem4(hSIRPA)SmocCd47em1(hCD47)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210020
Research Application:tumor research;inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Slamf7em(hSLAMF7)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18028
Research Application:Immunotherapy,Cancer research,Drug screening
Mice
Strain Name:C57BL/6Smoc-Slc7a5em(hSLC7A5)Smoc
Strain State:Developing | Cat. NO.:NM-HU-230020
Mice
Strain Name:C57BL/6Smoc-Smad2em1(hSMAD2)Smoc
Strain State:Developing | Cat. NO.:NM-HU-232899
Mice
Strain Name:C57BL/6Smoc-Smad3em1(hSMAD3)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-232900
Mice
Strain Name:C57BL/6Smoc-Smn1em1(hSMN2)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234022
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