Models

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:B6.129S-Lag3tm1(hLAG3)Ctla4em1(hCTLA4)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190018
Research Application:Immune-related
Mice
Strain Name:C57BL/6Smoc-Lair1em2(LAIR1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000011
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Lair1em2(LAIR1)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220040
Mice
Strain Name:C57BL/6Smoc-Ldlrtm1(hLDLR)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-230148
Mice
Strain Name:C57BL/6Smoc-Lect2tm1(hLECT2)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-233624
Mice
Strain Name:C57BL/6Smoc-Leprtm(hLEPR)Smoc
Strain State:Developing | Cat. NO.:NM-HU-230052
Mice
Strain Name:C57BL/6Smoc-Lgals9em(hLGALS9)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-215009
Mice
Strain Name:C57BL/6Smoc-Liftm(hLIF)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220506
Mice
Strain Name:C57BL/6Smoc-Tgtn(hLILRA4)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-225074
Mice
Strain Name:C57BL/6Smoc-Tg(hLILRB1-hLILRB4)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-TG-220022
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