Models

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Grin1tm1(hGRIN1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-234543
Mice
Strain Name:C57BL/6Smoc-Grin2atm1(hGRIN2A)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234544
Mice
Strain Name:C57BL/6Smoc-Grin2btm1(hGRIN2B)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234545
Mice
Strain Name:C57BL/6Smoc-Gucy2ctm(hGUCY2C)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220417
Mice
Strain Name:C57BL/6Smoc-Hao1tm2(hHAO1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-231908
Mice
Strain Name:C57BL/6Smoc-Hao1tm1(hHAO1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-231907
Mice
Strain Name:C57BL/6Smoc-Havcr1tm1(hHAVCR1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-233209
Mice
Strain Name:C57BL/6Smoc-Hbb-bt&Hbb-bstm1(hHBB)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000080
Research Application:Thalassemia research;drug screening
Mice
Strain Name:C57BL/6Smoc-hHBBem1E7VSmoc
Strain State:Developing | Cat. NO.:NM-KI-233577
Mice
Strain Name:C57BL/6Smoc-HBBem1(IVS2-654C>T)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-234585
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