Models

Conditional Knockouts

In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.

Mice
Strain Name:C57BL/6Smoc-Ccl27aem1(flox)Smoc
Strain State:Developing | Cat. NO.:NM-CKO-232110
Mice
Strain Name:C57BL/6Smoc-Ccl27bem1(flox)Smoc
Strain State:Developing | Cat. NO.:NM-CKO-232111
Mice
Strain Name:C57BL/6Smoc-Ccl28em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Ccl3em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-234047
Mice
Strain Name:C57BL/6Smoc-Ccl4em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-234048
Mice
Strain Name:C57BL/6Smoc-Ccl5em1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-2113267
Mice
Strain Name:C57BL/6Smoc-Ccl6em1(flox)Smoc
Strain State:Developing | Cat. NO.:NM-CKO-231944
Mice
Strain Name:C57BL/6Smoc-Ccl7em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-232266
Mice
Strain Name:C57BL/6Smoc-Ccl8em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-234049
Mice
Strain Name:C57BL/6Smoc-Ccl9em1(flox)Smoc
Strain State:Developing | Cat. NO.:NM-CKO-231945
Email Back to top