Models

Conditional Knockouts

In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.

Mice
Strain Name:C57BL/6Smoc-Atf2em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-240693
Mice
Strain Name:C57BL/6Smoc-Atf3em1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-2116117
Mice
Strain Name:C57BL/6Smoc-Atf4tm1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-240924
Mice
Strain Name:C57BL/6Smoc-Atf5em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-241111
Mice
Strain Name:C57BL/6Smoc-Atf6em1(flox)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-CKO-200080
Research Application:Research on signal transduction mediated by p38-alpha and p38-beta and Sertoli-Sertoli cell connection dynamics
Mice
Strain Name:C57BL/6Smoc-Atf6bem1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-231649
Mice
Strain Name:C57BL/6Smoc-Atf7tm(flox)/Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-220191
Mice
Strain Name:C57BL/6Smoc-Atf7ipem1(flox)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-CKO-205083
Mice
Strain Name:C57BL/6Smoc-Atf7ip2em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Atg10em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
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