Rare diseases are those that affect only a small percentage of the world’s population. Most rare diseases are genetic. We provide many gene-engineered mouse models which are helpful for new therapies exploration and orphan drug development.
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Strain Name：C57BL/6Smoc-Raf1em1(D486N)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200252
Research Application：Noonan syndrome
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Strain Name：B6;129S-Rag1tm1(loxP-EGFP-PolyA-loxP-Neo-loxP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00069
Research Application：Immunodeficiency,tumor-bearing model
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Strain Name：C57BL/6Smoc-Rag2em2Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190429
Disease Connection：ulcerative colitis, severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive
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Strain Name：B6;129S-Rag2tm1(loxP-EGFP-PolyA-loxP-Neo-loxP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00070
Research Application：Immunodeficiency,tumor-bearing model
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Strain Name：C57BL/6Smoc-Rb1tm1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-18012
Disease Connection：retinoblastoma, osteosarcoma, pancreatic carcinoma, medulloblastoma
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Strain Name：C57BL/6Smoc-Rbl2tm1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200029
Disease Connection：retinoblastoma
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Strain Name：C57BL/6Smoc-Sgceem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-210227
Disease Connection：myoclonic dystonia 11
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Strain Name：C57BL/6Smoc-Sh2d1aem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200730
Disease Connection：X-linked lymphoproliferative syndrome 1
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Strain Name：C57BL/6Smoc-Slc12a3em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-201063
Disease Connection：Gitelman syndrome
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Strain Name：C57BL/6Smoc-Slc34a1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200642
Disease Connection：hereditary hypophosphatemic rickets with hypercalciuria
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