The establishment of U-GEMM (yoUr Genetically Engineered Mouse Model) repository containing 6,000+ “off-shelf” proprietary sets the stage of entry into new possibilities in gene function, drug screening, and human disease research.
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Strain Name：C57BL/6Smoc-Calm1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-2108430
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Strain Name：C57BL/6Smoc-Calm1tm1(Flox-K22R-K95R-K116R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210348
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Strain Name：C57BL/6Smoc-Calm1em2(K22R,K95R,K116R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210238
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Strain Name：C57BL/6Smoc-Calm1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190703
Research Application：The encoded protein acts as a calcium sensor and is involved in relaying signals to calcium-sensitive proteins, enzymes and ion channels. The protein-calcium complex binds target proteins to regulate several cellular processes, including smooth muscle contraction, inflammation, apoptosis and the immune response. Mutations in the human gene are associated with catecholaminergic polymorphic ventricular tachycardia and long QT syndrome 14.
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