Mbp-KO(C3H)

Nomenclature

C3H/HeJSmoc-Mbpem1Smoc

Cat. NO.

NM-KO-226433

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Mbp

Model Description

通过敲除Mbp基因exon 5-9,建立Mbp基因敲除小鼠模型。

Validation Data

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Fig 1. The number of episodes during the EEG/EMG recording period in control mice (n=3) and Mbp-KO(C3H)  mice (n=6, 4-month old). *P<0.05, unpaired t test.

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Fig 2. Epileptiform discharges in Mbp-KO(C3H) mice. Representative electroencephalographic (EEG) (A-B)  and electromyographic (EMG) (C) traces of epileptiform discharges in Mbp-KO(C3H) mice (4-month old). Representative electroencephalographic (EEG) (D)  and electromyographic (EMG) (E) traces of C57 wildtype mice (4-month old).


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