C3-KO

Nomenclature

C57BL/6Smoc-C3em1Smoc

Cat. NO.

NM-KO-191193

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
C3

Model Description

Exon 2 of C3 gene was deleted to generate C3 knockout mice.
Research Application:Immune-related

Validation Data

image.png

Fig. 1 Detection of C3 expression in thymus by RT-PCR (male mice for both groups). 

Wild type: one band at 225 bp with primers F1/R1(mC3) and one band at 123 bp with primers F/R(mGapdh). 

Homozygous: no band with primers F1/R1(mC3) and one band at 123 bp with primers F/R(mGapdh). 

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig. 2 Detection of mouse C3 expression in serum by ELISA. (1 male WT C57BL/6 mouse and 3 male HO C3-KO mice)

Abbr.  HO, homozygous; WT, wild type; N.D. not detected.



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