Sftpc-IRES-CreERT2

An IRES-CreERT2 co-expression cassette is inserted into 3'UTR region of Sftpc gene via homologous recombination to establish a tamoxifen inducible Sftpc-CreERT2 tool stain. *This strain CreERT2 has leakage (see validation data for details), please select according to the purpose of the study。

Fig1. Cre mediated recombination in lung of SftpcCreERT2/+;Rosa26tdTomato/+ mouse.

Fig2. Detection of tdTomato(red) in various tissues of SftpcCreERT2/+;Rosa26tdTomato/+ mouse. Expression tissues include: lung epithelial cells, testis interstitial cells, salivary glands, muscles. Tissues that unexpressed include brain, spinal cord, retina, heart, liver, brown fat, thymus, kidney, pancreas, large and small intestine, spleen, and skin.(2-months old, male) (For more detailed information please contact our technical advisor.)