Cyp19a1-2A-CreERT2

Nomenclature

C57BL/6Smoc-Cyp19a1em1(2A-CreERT2)Smoc

Cat. NO.

NM-KI-251511

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Cyp19a1

Synonyms

Ar; ArKO; Int5; Cyp19; Int-5; p450arom

NCBI ID

13075

MGI ID

88587

Ensembl ID

ENSMUSG00000032274

Pubmed

Cyp19a1

Human Ortholog

CYP19A1

Model Description

The 2A-CreERT2 expression cassette was knocked into the Cyp19a1 gene stop codon site.

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Validation Data

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Fig1. CreERT2 mediated recombination in testicle of Cyp19a1CreERT2/+; Rosa26tdTomato/+ mouse. 

Cyp19A1-2A-CREert2.jpg

Fig2. Detection of tdTomato(red) in various tissues of Cyp19a1CreERT2/+; Rosa26tdTomato/+ mouse. 

Organs and tissues with tdTomato expression following tamoxifen induction include:  brain, large intestine, salivary gland, reproductive system, and adrenal gland.

Organs and tissues without tdTomato expression following tamoxifen induction include:Small intestine, stomach, liver, lung, spleen, skin, pancreas, kidney, eyeball.(65-days old, male) (For more detailed information please contact our technical advisor.) 


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