Hlf-CreERT2

Nomenclature

C57BL/6Smoc-Hlfem1(CreERT2)Smoc

Cat. NO.

NM-KI-230441

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Hlf

Synonyms

E230015K02Rik

NCBI ID

217082

MGI ID

96108

Ensembl ID

ENSMUSG00000003949

Pubmed

Hlf

Human Ortholog

HLF

Model Description

CreERT2 expression cassette was knocked into the Hlf gene .

Validation Data

image.png

Fig1. CreERT2 mediated recombination in liver of HlfCreERT2/+; Rosa26tdTomato/+ mouse. 

R1-8812 HIF-CreERT2.jpgFig2. Detection of tdTomato(red) in various tissues of HlfCreERT2/+; Rosa26tdTomato/+ mouse. 

After tamoxifen induction, tdTomato was expressed in the brain, spinal cord, eyeballs, heart, liver, lungs, stomach, salivary glands, brown adipose tissue, adrenal glands, kidneys, pancreas, large intestine, small intestine, spleen, reproductive organs, muscle, skin, and thymus.

Tissues with expression leakage in the uninduced group: brain, eyeballs, brown adipose tissue, adrenal glands, kidneys, and muscle..(57-days old, male and female) (For more detailed information please contact our technical advisor.) 



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