Sftpc-IRES-rtTA

Nomenclature

C57BL/6Smoc-Sftpcem2(Avitag-IRES-V5-M2rtTA-WPRE-polyA)Smoc

Cat. NO.

NM-KI-18043

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Sftpc

Synonyms

SP5; SPC; SP-C; Sftp2; Bricd6; Sftp-2; pro-SpC

NCBI ID

20389

MGI ID

109517

Ensembl ID

ENSMUSG00000022097

Pubmed

Sftpc

Human Ortholog

SFTPC

Model Description

An Avitag-IRES-V5-M2rtTA-WPRE-polyA expression cassette was knocked into the Sftpc gene stop codon site by homologous recombination.

Validation Data

sftpc-1.png

Fig1. Expression Pattern of EGFP in Sftpc -M2rtTA; pTRE-H2BGFP mice.

Sftpc -M2rtTA mice express the reverse tetracycline-controlled transactivator (rtTA) protein under the control of the mouse surfactant, pulmonary-associated protein C (Sftpc) promoter, and expression of the target gene may be regulated by the tetracycline analog, doxycycline. This strain provides a Tet-On tool that allows the inducible expression of genes in the developing and adult lung and respiratory epithelium.

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