Tubb3-2A-CreERT2-2A-tdTomato
Nomenclature
C57BL/6Smoc-Tubb3em1(P2A-CreERT2-T2A-tdTomato-WPRE-pA)Smoc
Cat. NO.
NM-KI-240472
Strain State
Repository Live
Gene Summary
Gene Symbol
Tubb3
Model Description
Genotyping Protocol
Validation Data
Fig1. CreERT2 mediated recombination in cerebellum of Tubb3CreERT2/+; Rosa26zsGreen/+ mouse.
Fig2. CreERT2 mediated recombination in DRG of Tubb3CreERT2/+; Rosa26zsGreen/+ mouse.
Fig3. Detection of zsGreen(Green) and tdTomato(red) in various tissues of Tubb3CreERT2/+; Rosa26zsGreen/+ mouse.
Following tamoxifen induction, tissues expressing zsGreen included the brain, spinal cord, reproductive system, skin, pituitary gland and dorsal root ganglia. Tissues with low levels of zsGreen expression included the heart, lung, and liver.
In the absence of tamoxifen induction, low-level leaky expression of zsGreen was observed in the brain, spinal cord, dorsal root ganglia, and pituitary gland.
Regarding tdTomato, minor expression was observed in the brain, while no obvious expression was detected in other tissues.
(31-days old, male) (For more detailed information please contact our technical advisor.)
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