Trp53-Flox

Nomenclature

C57BL/6Smoc-Trp53tm2(flox)Smoc

Cat. NO.

NM-CKO-18005

Strain State

Repository Live

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Gene Summary

Gene Symbol
Trp53

Synonyms

bbl; bfy; bhy; p44; p53; Tp53

NCBI ID

22059

MGI ID

98834

Ensembl ID

ENSMUSG00000059552

Pubmed

Trp53

Human Ortholog

TRP53

Model Description

These Trp53 flox mice possess loxP sites flanking exons 5-7 via ESC targeting. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.
Research Application：cancer research

Publications

Chromatin Remodeling Induced by ARID1A Loss in Lung Cancer Promotes Glycolysis and Confers JQ1 Vulnerability
References：CANCER RESEARCH

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