Rag2/Il2rg-KO/hIL3/hCSF2/hCSF1/hTHPO/hSIRPA

Nomenclature

C57BL/6Smoc-Rag2emIl2rgemIl3tm1(hIL3)Csf2tm1(CSF2)Csf1tm2(CSF1)Thpotm1(hTHPO)Sirpatm2(hSIRPA)Smoc

Cat. NO.

NM-XA-234933

Strain State

Repository Live

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Gene Summary

Gene Symbol
SIRPA

Synonyms

Bit; P84; SIRP; SHP-1; CD172a; Ptpns1; SHPS-1; AI835480

NCBI ID

19261

MGI ID

108563

Ensembl ID

ENSMUSG00000037902

Pubmed

SIRPA

Human Ortholog

SIRPA

Model Description

The hTHPO/hSIRPA(NM-XA-234931) was crossed with Rag2/Il2rg-KO/hIL3/hCSF2/hCSF1(NM-XA-234932) to generate Rag2/Il2rg-KO/hIL3/hCSF2/hCSF1/hTHPO/hSIRPA mice.

Validation Data

image.png

Fig.1 Detection of immune cell subpopulations in the blood of WT C57BL/6, M-NSG and MISTRG (HO Rag2/Il2rg-KO/hIL3/hCSF2/hCSF1/hTHPO/hSIRPA) mice. (WT C57BL/6: 13 weeks old, male; M-NSG: 13 weeks old, male; MISTRG: 17 weeks old, male)

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