hAGT/hREN

Nomenclature

C57BL/6Smoc-Agttm1(hAGT)Ren1tm(hREN)Smoc

Cat. NO.

NM-HU-234349

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Ren1

Synonyms

Ren; Rnr; Rn-1; Ren-1; Ren-A; Ren1c; Ren1d; D19352

NCBI ID

19701

MGI ID

97898

Ensembl ID

ENSMUSG00000070645

Pubmed

Ren1

Human Ortholog

REN1

Model Description

The hREN(2)(NM-HU-220370) was crossed with hAGT(NM-HU-225082) to generate hAGT/hREN mice.

Validation Data

image.png

Fig.1 Detection of AGT(A) and REN(B) expression in liver by RT-PCR. 

Wild type: only one band at 232 bp with primers F1/R1(mAgt); only one band at 235 bp with primers F3/R4(mRen);

Homozygous: only one band at 360 bp with primers F2/R2(hAGT); only one band at 202 bp with primers F4/R4(hREN)

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hAGT and mAGT expression in plasma by ELISA (male, n=3, 7-8wks). 

Abbr. HO, homozygous; WT, wild type.

image.png

Fig.3 Detection of hREN expression in plasma by ELISA (male, n=3, 7-8wks). 

Abbr. HO, homozygous; WT, wild type.

image.png

Fig.4 Detection of mANG2 expression in plasma by ELISA (male, n=3, 7-8wks). 

Abbr. HO, homozygous; WT, wild type.

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