hCCL17

Nomenclature

C57BL/6Smoc-tm1(hCCL17)Smoc

Cat. NO.

NM-HU-240097

Strain State

Embryo cryopreservation

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Model Description

The endogenous mouse gene was replaced by human CCL17 gene.

Validation Data

image.png

Fig.1 Detection of CCL17 expression in lung by RT-PCR. 

Wild type: only one band at 157 bp with primers F1/R1(mCcl17);

Heterozygous: one band at 157 bp with primers F1/R1(mCcl17) and one band at 160 bp with primers F2/R2(hCCL17). 

Abbr. M, DNA marker;  HE, heterozygous; WT, wild type.

image.png

Fig.2 Detection of mCCL17(A) and hCCL17(B) expression in serum by ELISA (n=3). 

Abbr.  HO, homozygous; WT, wild type; N.D. not detected.

Note. The hCCL17 and C57BL/6 mice were i.p. injected with LPS for 2h.


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