hASGR1

Fig.1 Detection of ASGR1 expression in liver by RT-PCR. 

Wild type: only one band at 224 bp with primers F1/R1(mAsgr1);

Homozygous: only one band at 326 bp with primers F2/R2(hASGR1).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

Fig.2 Detection of human ASGR1 expression in hASGR1 mice by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous; NC, negetive control, blank.

Fig.3 Body weight and ratios of liver to body weight of hASGR1 knockin mice. (n=4-5, 7-8-week-old, Mean±SEM, Unpaired t-test, ns: no significant)

Abbr. HO, homozygous; WT, wild type.

Table 1. Biochemical test of serum from hASGR1 knockin mice. Values are expressed as mean±SEM.

Abbr. HO, homozygous; WT, wild type.