Abcb1a/Abcb1b-KO(FVB)
Nomenclature
FVB-Abcb1aem1Abcb1bem1Smoc
Cat. NO.
NM-KO-191211
Strain State
Repository Live
Model Description
All sequences between exon2 of Abcb1a gene and exon28 of Abcb1b gene were knocked out by CRISPR/Cas9 technology.
*Literature published using this strain should indicate: Abcb1a/Abcb1b-KO(FVB) mice (Cat. NO. NM-KO-191211) were purchased from Shanghai Model Organisms Center, Inc..
Validation Data
Fig1. In vivo PK profiles of Digoxin in FVB and Abcb1a/Abcb1b-KO mice (male, 6-8 weeks, n=6).
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