Trp53-KO
Nomenclature
B6.129-Trp53tm1Smoc
Cat. NO.
NM-KO-00011
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
Trp53
Model Description
A neo cassette replaces exons 2-11,including the start codon,of Trp53 (transformation related protein 53).Null homozygotes show high, early-onset tumor incidence;some have persistent hyaloid vasculature and cataracts.
Research Application：Tumorigenesis，aging，antineoplastic drug evaluation etc
*Literature published using this strain should indicate: Trp53-KO mice (Cat. NO. NM-KO-00011) were purchased from Shanghai Model Organisms Center, Inc..
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