Pdx1-2A-Cre

Nomenclature

C57BL/6Smoc-Pdx1em(2A-Cre)1Smoc

Cat. NO.

NM-KI-225082

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
pdx1

Synonyms

Ipf1， IDX-1， IPF-1， Mody4， STF-1， pdx-1

NCBI ID

18609

MGI ID

102851

Ensembl ID

ENSMUSG00000029644

Pubmed

pdx1

Model Description

2A-Cre expression cassette was knocked into the Pdx1 gene .

Validation Data

image.png

Fig1. Cre mediated recombination in pancreasof Pdx1Cre/+;Rosa26tdTomato/+ mice.

The white dashed line indicates the islets of langerhans.

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Fig2. Cre mediated recombination in brunner's glands  of Pdx1Cre/+;Rosa26tdTomato/+ mice.

image.png

Fig3. Detection of tdTomato(red) in various tissues of of Pdx1Cre/+;Rosa26tdTomato/+ mouse. Expression tissues include: pancreas, lung, small intestine, kidney, colon. A few cells expressing it were also identified in the liver, adrenal gland, muscle, thymus, subcutaneous tissue. Tissues that unexpressed include:brain, retina, heart, stomach, salivary glands, brown fat, spinal cord, spleen, testis, epidermis, pituitary gland.

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