hGFRAL(BALB/c)

Nomenclature

BALB/cAnSmoc-Gfraltm(hGFRAL)Smoc

Cat. NO.

NM-HU-220537

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Gfral

Model Description

The endogenous mouse Gfral gene was replaced by human GFRAL gene.

Validation Data

image.png

Fig.1 Detection of GFRAL expression in cerebellum by RT-PCR. 

Wild type: only one band at 270 bp with primers F1/R1(mGfral);

Homozygous: only one band at 372 bp with primers F2/R2(hGFRAL).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human GFRAL expression in hGFRAL(BALB/c) knockin mice by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous; PC, positive control, Hela cell.

Note. The anti-human GFRAL antibody cross-reacted with mouse GFRAL and humanized GFRAL. Specific bands for human GFRAL were at approximately 26 and 45 kDa.


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