hTNFR2(BALB/c)
Nomenclature
BALB/cAnSmoc-Tnfrsf1btm(hTNFRSF1B)Smoc
Cat. NO.
NM-HU-220499
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
TNFRSF1B
Model Description
Validation Data
Fig.1 Expression analysis of hTNFR2 on Treg cells in spleen of hTNFR2(BALB/c) humanized mice.
Leukocytes were collected from spleen of wild-type BALB/c mice (female, 8 weeks) and homozygous hTNFR2(BALB/c) mice (male, 14 weeks) stimulated in vivo with anti-CD3ε and analyzed by flow cytometry with anti-mTNFR2 and anti-hTNFR2. hTNFR2 were exclusively detectable in hTNFR2 humanized mice but not in wild-type mice.
Fig.2 Expression analysis of hTNFR2 on DCs, monocyte, B cells, and neutrophils in spleen of hTNFR2(BALB/c) humanized mice.
Leukocytes were collected from spleen of wild-type balb/c mice (female, 12 weeks) and homozygous hTNFR2(BALB/c) mice (male, 18 weeks), and analyzed by flow cytometry with anti-mTNFR2 and anti-hTNFR2. hTNFR2 were exclusively detectable in hTNFR2 humanized mice but not in wild-type mice.
Fig.3 Expression analysis of hTNFR2 on monocyte, B cells, and neutrophils in blood of hTNFR2(BALB/c) humanized mice.
Leukocytes were collected from blood of wild-type balb/c mice (female, 12 weeks) and homozygous hTNFR2(BALB/c) mice (male, 18 weeks), and analyzed by flow cytometry with anti-mTNFR2 and anti-hTNFR2. hTNFR2 were exclusively detectable in hTNFR2 humanized mice but not in wild-type mice.
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