In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.
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Strain Name：C57BL/6Smoc-Zfp740em1(flox)Smoc
Strain State：Developing | Cat. NO.：NM-CKO-260422
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Strain Name：C57BL/6JSmoc-Zfp746em1(flox)Smoc
Strain State：Developing | Cat. NO.：NM-CKO-261380
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Strain Name：C57BL/6Smoc-Zfp748em1(flox)Smoc
Strain State：Developing | Cat. NO.：NM-CKO-260752
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Strain Name：C57BL/6JSmo-Zfp750em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-2102841
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Strain Name：C57BL/6JSmo-Zfp758em1(flox)Smoc
Strain State：Developing | Cat. NO.：NM-CKO-261826
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Strain Name：C57BL/6Smoc-Zfp759em1(flox)Smoc
Strain State：Developing | Cat. NO.：NM-CKO-260793
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Strain Name：C57BL/6Smoc-Zfp760em1(flox)Smoc
Strain State：Developing | Cat. NO.：NM-CKO-260414
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