MC38-hTROP2
Strain Information
Validation Data
Ⅰ.In vitro Expression of MC38-hTROP2 cell line
The hTROP2 protein expression in the wild-type MC38 and MC38-hTROP2 cells were measured by Flow Cytometry.
Figure 1. hTROP2 expression in wild-type MC38 and MC38-hTROP2 cell lines
Ⅱ.Characterization of in vivo growth kinetics
To test the take rates, and the tumor growth characteristics of MC38-hTROP2 cell line, cells were subcutaneously inoculated into the C57BL/6 mice.
Figure 2. Tumor growth curve of MC38-hTROP2 syngeneic model
Figure 3. Body weight change of MC38-hTROP2 syngeneic model
Ⅲ.Expression of hTROP2 protein in tumors
To verify the hTROP2 protein expression, the tumors were dissected and separated for single cell suspension.
Figure 4. The expression of hTROP2 in humanized modified tumors by FACS
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