MC38-hB7H3

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Strain Information

Cell Line

MC38-Cd276em1(hB7H3)/Smoc

Cat. NO.

NM-S13-TM06

Model Description

The endogenous mouse Cd276(also known as B7h3)  gene was replaced by human B7H3 gene. 

Strain State

Validation of tumorigenic capacity completed

Validation Data

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Figure 1. hB7H3 expression in wild-type MC38 and MC38-hB7H3 cell lines.

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Figure 2. Tumor growth curve of MC38-hB7H3 syngeneic model (n=5).

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Figure 3. Body weight change of MC38-hB7H3 syngeneic model (n=5).

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Figure 4. The expression of hB7H3 in humanized modified tumors by FACS.


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