R26-CAG-Luc-2A-tdTomato(NMG)
Nomenclature
NOD-PrkdcscidIl2rgem1Gt(ROSA)26Sorem1(CAG-Luciferase-2A-tdTomato-WPRE-pA)
Cat. NO.
NM-KI-233090
Strain State
Developing
Gene Summary
Gene Symbol
Gt(ROSA)26Sor
Model Description
The CAG-Luciferase-2A-tdTomato-WPRE-pA expression cassette was knocked into the R26 locus.
鉴定方案
Validation Data
Fig.1 Detection of tdTomato expression in blood by FACS.
The result showed that most of all CD45+ cells in R26-CAG-Luc-2A-tdTomato(NMG) mice blood are tdTomato+ cells. (female, WT: 8.6wks, HE: 9.6wks)
Fig.2 Detection of tdTomato fluorescence by IVIS imaging system. (female, WT: 8.6wks, HE: 9.6wks)
Fig.3 Detection of tdTomato expression in multiple tissues.
The results showed that tdTomato expressed in a variety of tissues in heterozygous R26-CAG-Luc-2A-tdTomato(NMG) mice, including the pancreas, mammary gland, lung, liver, kidney, large intestine, muscle and skin.
You may also like
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreAt GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
Learn more