R26-CAG-LSL-Ythdc2-IRES-EGFP

Nomenclature

C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-Ythdc2-3xFLAG-IRES-EGFP)Smoc

Cat. NO.

NM-KI-190060

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Gt(ROSA)26Sor

Model Description

These mice harbor a CAG-LSL-Ythdc2-3xFLAG-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination.
Research Application:mRNA methylation

Validation Data

R26.png

Fig1.  Validation of EGFP expression in R26-Ythdc2-3xFlag-IRES-EGFP +/-;Dppa3-Cre +/- mice by fluorescence microscope. These results showed that EGFP can be expressed in the brain,heart,liver,lung and kidney and brain of R26-Ythdc2-3xFlag-IRES-EGFP +/-;Dppa3-Cre +/- mice.

R26-2.png

Fig2. Validation of Ythdc2 expression in R26-Ythdc2-3xFlag-IRES-EGFP+/-;Dppa3-Cre+/- mice by Western blot. These results showed that Ythdc2 can be expressed in the heart, liver, spleen, lung, kidney and brain of R26-Ythdc2-3xFlag-IRES-EGFP+/-;Dppa3-Cre+/- mice.


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