Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.
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mouse
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Strain Name:C57BL/6JSmo-Gucy1a1em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-201164
Disease Connection:primary open angle glaucoma
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mouse
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mouse
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Strain Name:C57BL/6JSmo-Gucy1a3em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-210339
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mouse
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mouse
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Strain Name:C57BL/6JSmo-Gucy2cem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200241
Disease Connection:obesity
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mouse
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Strain Name:C57BL/6JSmo-Gucy2cem2Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-226124
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mouse
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mouse
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Strain Name:C57BL/6JSmo-Gucy2eem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200984
Disease Connection:Leber congenital amaurosis 1, cone-rod dystrophy 6
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mouse
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Strain Name:C57BL/6Smoc-Gucy2Fem1Smoc
Strain State:Developing | Cat. NO.:TBD
Disease Connection:Leber congenital amaurosis 1
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mouse
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