Models

Knockouts

Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.

mouse
Strain Name:C57BL/6JSmo-Gnmtem1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-200976
Disease Connection:glycine N-methyltransferase deficiency, hepatocellular carcinoma
mouse
Strain Name:C57BL/6JSmo-Gnpatem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-201285
Disease Connection:disease of mental health, rhizomelic chondrodysplasia punctata type 2
mouse
Strain Name:C57BL/6Smoc-Gnpda1em1Smoc
Strain State:Developing | Cat. NO.:TBD
mouse
Strain Name:C57BL/6JSmo-Gnpda2em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-2112053
mouse
Strain Name:C57BL/6JSmo-Gnptabem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-201104
Disease Connection:mucolipidosis II alpha/beta
mouse
Strain Name:C57BL/6Smoc-Gnptgem1Smoc
Strain State:Developing | Cat. NO.:TBD
mouse
Strain Name:C57BL/6JSmo-Gnrhrem1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-200228
Research Application:Therapeutic antibody target
mouse
Strain Name:C57BL/6JSmo-Gnsem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-201161
Disease Connection:mucopolysaccharidosis III
mouse
Strain Name:C57BL/6Smoc-Golga1em1Smoc
Strain State:Developing | Cat. NO.:TBD
mouse
Strain Name:C57BL/6JSmo-Golga2em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-201615
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