Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.
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Strain Name：C57BL/6Smoc-Gja8em1Smoc
Strain State：Developing | Cat. NO.：TBD
Disease Connection：cataract 1 multiple types
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Strain Name：C57BL/6JSmo-Gjb1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-241473
Disease Connection：hypomyelinating leukodystrophy 2, Charcot-Marie-Tooth disease X-linked dominant 1
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Strain Name：C57BL/6JSmo-Gjb4em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201606
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Strain Name：C57BL/6JSmo-Gjb5em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-232768
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Strain Name：C57BL/6JSmo-Gjb6em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190962
Disease Connection：autosomal recessive nonsyndromic deafness 1A
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Strain Name：C57BL/6JSmo-Gjc2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-201607
Disease Connection：hypomyelinating leukodystrophy 2
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Strain Name：C57BL/6JSmo-Gjc3em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190282
Research Application：Immune-related
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Strain Name：C57BL/6JSmo-Gjd4em/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-230208
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