Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.
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Strain Name：C57BL/6JSmo-Fads2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-201558
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Strain Name：C57BL/6JSmo-Faf1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-191163
Research Application：Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems.
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Strain Name：C57BL/6JSmo-Faf2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-2108775
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Strain Name：C57BL/6JSmo-Fahem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-191202
Disease Connection：tyrosinemia type I
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