Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.
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Mice
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Strain Name:C57BL/6JSmo-Efna4em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200169
Research Application:Therapeutic antibody target
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Mice
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Strain Name:C57BL/6Smoc-Efna5em1Smoc
Strain State:Developing | Cat. NO.:TBD
Disease Connection:anencephaly
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Mice
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Mice
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Mice
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Mice
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Strain Name:C57BL/6JSmo-Efsem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200950
Disease Connection:Crohn's disease
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Mice
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Strain Name:C57BL/6JSmo-Egfem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190630
Research Application:certain cancers
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Mice
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Mice
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Strain Name:C57BL/6JSmo-Egfl6em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-200170
Research Application:Therapeutic antibody target
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Mice
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Strain Name:C57BL/6JSmo-Egfl7em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-226262
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