Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.
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Strain Name：C57BL/6JSmo-Cyb5d2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200145
Research Application：Therapeutic antibody target
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Strain Name：C57BL/6JSmo-Cyb5r3em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-251469
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Strain Name：C57BL/6JSmo-Cyb5r4em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200941
Disease Connection：type 2 diabetes mellitus
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Strain Name：C57BL/6JSmo-Cybaem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191171
Research Application：Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD)
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Strain Name：C57BL/6JSmo-Cybbem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18031
Disease Connection：chronic granulomatous disease, systemic lupus erythematosus
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