Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.
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Strain Name：C57BL/6Smoc-Crb1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190946
Research Application：Visual, retinopathy, photoreceptor cell development
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Strain Name：C57BL/6Smoc-Crb2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-232665
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Strain Name：C57BL/6Smoc-Crbnem1(I391V)Rag2em2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210398
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Strain Name：C57BL/6Smoc-Crbnem1Smoc
Strain State：Developing | Cat. NO.：TBD
Disease Connection：autosomal recessive non-syndromic intellectual disability
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Strain Name：C57BL/6Smoc-Creb1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190947
Research Application：Nervous system, circadian rhythm, long-term memory, fear, sensory neurons, etc.
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Strain Name：C57BL/6Smoc-Creb3em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-232797
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