Models

Knockouts

Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.

Mice
Strain Name:C57BL/6Smoc-Cldn14em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200837
Disease Connection:autosomal recessive nonsyndromic deafness 29
Mice
Strain Name:C57BL/6Smoc-Cldn15em1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Cldn16em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200632
Disease Connection:renal hypomagnesemia 3
Mice
Strain Name:C57BL/6Smoc-Cldn17em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-2112869
Mice
Strain Name:C57BL/6Smoc-Cldn18em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200124
Research Application:Therapeutic antibody target
Mice
Strain Name:C57BL/6Smoc-Cldn19em1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Cldn2em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-200125
Research Application:Therapeutic antibody target
Mice
Strain Name:C57BL/6Smoc-Cldn20em1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Cldn23em1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Cldn24em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-241914
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