Models

Knockouts

Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.

Mice
Strain Name:C57BL/6Smoc-Tlr12em1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6JSmo-Tlr13em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-241687
Mice
Strain Name:C57BL/6JSmo-Tlr2em1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-18026
Research Application:Immune-related
Mice
Strain Name:C57BL/6JSmo-Tlr3em2Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-190431
Research Application:Immune-related
Mice
Strain Name:BALB/cJSmo-Tlr3em2Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-210021
Mice
Strain Name:C57BL/6JSmo-Tlr4em1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-18052
Disease Connection:pulmonary emphysema
Mice
Strain Name:C57BL/6JSmo-Tlr5tm1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-18059
Research Application:Immune-related
Mice
Strain Name:C57BL/6JSmo-TLR6em1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-190195
Research Application:Immune-related
Mice
Strain Name:C57BL/6JSmo-Tlr7em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-190166
Research Application:Immune-related
Mice
Strain Name:BALB/cJSmo-Tlr7em4Smoc
Strain State:Developing | Cat. NO.:NM-KO-200646
Research Application:Research on Th1 differentiation pathway and Toll-like receptor signal transduction pathway
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