Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.
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Strain Name：C57BL/6JSmo-Slx4em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-201340
Disease Connection：Fanconi-like syndrome
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Strain Name：C57BL/6JSmo-Smad3em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190149
Research Application：Immune-related
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Strain Name：C57BL/6Smoc-Smad9em1Smoc
Strain State：Developing | Cat. NO.：TBD
Disease Connection：primary pulmonary hypertension
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Strain Name：C57BL/6JSmo-Smarca1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-2100277
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