Models

Knockouts

Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.

mouse
Strain Name:C57BL/6Smoc-Slc6A21em1Smoc
Strain State:Developing | Cat. NO.:TBD
mouse
Strain Name:C57BL/6JSmo-Slc6A3em1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-191034
Disease Connection:schizophrenia
mouse
Strain Name:C57BL/6JSmo-Slc6a4em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-200892
Disease Connection:autism spectrum disorder
mouse
Strain Name:C57BL/6JSmo-Slc6a6emSmoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-210164
mouse
Strain Name:C57BL/6Smoc-Slc6A7em1Smoc
Strain State:Developing | Cat. NO.:TBD
mouse
Strain Name:C57BL/6JSmo-Slc6A8em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-2111527
Disease Connection:creatine transporter deficiency
mouse
Strain Name:C57BL/6JSmo-Slc7a10em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-250320
mouse
Strain Name:C57BL/6JSmo-Slc7a11em2Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-231717
mouse
Strain Name:C57BL/6JSmo-Slc7A12em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-2108953
mouse
Strain Name:C57BL/6Smoc-Slc7A13em1Smoc
Strain State:Developing | Cat. NO.:TBD
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